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Myelogenous Leukemia: Causes, Symptoms, Treatment

Myeloid leukemia is a disease that causes the loss of blood cells, which are called granulocytes. For diseases characterized by uncontrolled growth of granulocytes, but this type of growth is completely dependent on the phase of the disease.

Myelogenous Leukemia: Causes, Symptoms, Treatment

It should be noted that chronic myelogenous leukemia a one type of myeloproliferative neoplasm, but, it provided in a separate unit for the classification. This pathology is a chromosomal mutation, which was called "Philadelphia chromosome".

Reasons of myeloid leukemia

  • The main cause of this disease, is believed to be exposure to ionizing radiation among scientists.
  • There is speculation that the development abnormalities may affect some chemicals that enter the body, viruses, alcohols, epoxies, alkenes, ketones, and so forth.
  • In addition, we have shown that smoking when suffering from chronic myeloid leukemia is uncontrolled, it can result in significant sharp deterioration in the patient's condition and even lead to death in some cases.
  • To date, the research that aimed to determine the causes that cause the disease and its progression continues.

Symptoms of myeloid leukemia

The first stage of chronic myeloid leukemia usually occurs without specific symptoms. But in some cases, the patient may complain about general deterioration:

  • Weakness.
  • Fatigue.
  • Excessive sweating.
  • Decreased appetite.
  • Bleeding.
  • Frequent colds and viral.
  • Pain in the heart.
  • Headaches.

Once the disease enters the stage of growth of clinical signs, ie acceleration phase, the patient may complain about the following symptoms:

  • Heaviness in the heart and stomach.
  • Bone and joint pain.
  • Bleeding that is difficult to stop.
  • An increase in temperature.

When the disease  reaches the blastic phase, the symptoms become pronounced, thrombosis and even heart attacks may occur.

Myeloid leukemia treatment

Most often, chronic myelogenous leukemia is diagnosed incidentally during investigations for other diseases or during a routine medical examination. To confirm the diagnosis, it is necessary to pass additional tests, usually a cytogenetic study of bone marrow cells.

The basic method of treatment of this pathology is a chemotherapy with using combined preparations, which can inhibit the activity of the blast cells.

It is understood that it is difficult to achieve sustained remission with chemotherapy only. Around 70% of bone marrow transplantation leads to a complete recovery.

Doctor's advice

  • No doubt, like all cancers, myeloid leukemia is categorized as severe pathologies that are difficult to correct.
  • It is important to diagnose the disease and begin active treatment
  • Even bone marrow transplantation allows to achieve 90% in the first year after diagnosis, each subsequent year, this percentage is significantly reduced.

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MTEC 2019 (eng.-com)