Wasps Help Scientists To Fight Breast Cancer
Employees of the Barcelona Biomedical Research Institute successfully tested wasp venom as a cancer treatment in cell cultures. It is no secret that the usual anticancer drugs bring significant side effects. Moreover, cancer is able to adjust to them, developing resilience.
From this perspective, the peptide out of wasp venom looks like a very promising development. This peptide is clinging to a few amino acids. This feature lets it destroy breast cancer cells. Peptide forms holes in the cell membrane, enters the cell, causing its death, provoking apoptosis (programmed death of the cell) or necrosis.
But such approach has certain limitations. Wasp venom is particularly toxic. Plus, it’s aggressive to all cells in the body. Therefore, researchers has to to work on the method of delivering the peptide directly to tumors, bypassing the healthy tissue. The proposed method is based on the polymer carrier. It concludes the peptide bound to the receptor of cancer cells, and cytotoxic peptide from the wasp venom. In such case compounds get distributed right into the cancer cells without affecting healthy ones. In the closest future, scientists hope to test the approach with mice.